Faculty of Science

Department of Pharmacy

Research Funding

Year

Total Number of Grants
(External Grants)

Singapore $

Jan-Apr 2013

5 (3)

1,545,407.00

2012

9(7)

4,682,517.00

2011

10 (10)

6,010,395.10

2010

14 (6)

4,330,932.00

2009

10 (5)

3,174,625.14

2008

9 (4)

1,849,382.27

2007

11 (3)

2,343,813.35

2006

16 (1)

2,495,288.00

2005

8 (2)

872,676.74

2004

8 (1)

563,314.00

2003

9 (1)

988,839.00

2002

8 (3)

977,089.31

2001

6 (0)

395,600.00

2000

9 (0)

920,955.00

1999

3 (0)

97,600.00

1998

3 (0)

177,300.00

1997

9 (1)

2,999,673.85

1996

1 (1)

2,212,892.07

Total

148 (49)

36,668,299.83

 

PROJECT TITLE

PERIOD

AMOUNT

In Search of Novel Neuroactive Compounds Through Design and Synthesis

NSTB/17/4/12
R-148-000-005-305
01.04.96–30.11.00

$2,212,892.07
NTL, CWK, JCT,
PWong (Pharmacol)
Ng TP (Chem)

1996

Sub-Total

$2,212,892.07

GEA-NUS Pharmaceutical Processing Research Laboratory

NSTB/17/4/21
R-148-000-006-305)
01.06.97–31.05.02

$1,931,529.85
PHeng

Design and development of transdermal therapeutic systems for peri-operative applications

1997-2000
R-148-000-008-112

$175,866
CSY

Novel inhibitors of DHFR as therapeutic agents

1997-2000
R-148-000-009-112

$36,580
CWK

Pharmacokinetic and pharmacodynamic drug interaction studies with warfarin in the rat

1997-2000
R-148-000-010-112

$174,300
EC

Development of immunoassays for detection of catecholamine secreting tumours

1997-2000
R-148-000-011-112

$144,798
PHo

Pharmacokinetics of cefazolin in continuous ambulatory peritoneal dialysis hemodialysis (CAPD) and hemodialysis patients

1997-2000
R-148-000-012-112

$59,000
LCL

Local delivery systems of anti-microbial agents in the treatment of peridontal disease

1997-2000
R-148-000-013-112

$153,900
CLW

Synthesis and evaluation of oximes and related compounds as neuroactive agents

1997-2000
R-148-000-014-112

$175,900
GML

Analysis of Chinese proprietary medicine (CPM) : Undeclared Drugs & Known Active Ingredients

1997-2000
R-148-000-015-112

$147,800
KHL

1997

Sub-Total

$2,999,673.85

Synthesis & evaluation of potential antimalarial compounds

1998-2001
R-148-000-016-112

$48,000
GML

Population pharmacokinetics of aminoglycosides, digoxin & cyclosporine

1998-2001
R-148-000-017-112

$46,600
LCL

Chitosan-alginate membranes

1998-2000
R-148-000-019-112

$82,700
LLY

1998

Sub-Total

$177,300.00

Application of pharmacoeconomic principles in hospital formulary selection

1999-2001
R-148-000-018-112

$7,600
LSC

A pilot study on pharmacokinetics of antidepressants with lactation

1999-2002
R-148-000-020-112

$30,000
Eli Chan

Biopharmaceutics of therapeutic agents

1999-2001
R-148-000-021-112

$60,000
PHo

1999

Sub-Total

$97,600.00

Structural studies of T-cell adhesion inhibitory peptides

2000-2002
R-148-000-022-112

$62,000
SJ

Polymer nanospheres for drug delivery

2000-2003
R-148-000-023-112

$123,300
LLY

A study of the process of spray congealing for developing controlled release products

2000-2002
R-148-000-024-112

$160,000
P Heng

Development of neuroprotective agents through the intervention of nitric oxide synthase activity

2000-2003
R-148-000-025-112

$81,910
CWK

Design of b-turn peptides from CD2 as therapeutic agents for autoimmune diseases

2000-2002
R-148-000-026-112

$64,830
SJ

Bioactive peptides with cardiovascular properties

2000-2002
R-148-000-027-112

$178,055
GML

Pharmacokinetics and pharmacodynamics of analgesics in the control of pain

2000-2002
R-148-000-028-112

$65,000
PHo

Investigations of phytochemical agents for wound healing

2000-2001
R-148-000-029-112

$106,100
CSY

Analysis of Chinese herbal medicine : Profiling

2000-2004
R-148-000-030-112
R-148-000-030-107

$79,760
KHL

2000

Sub-Total

$920,955.00

Defining the Peptide Binding Sites on ICAM-1 Protein/(PS)10047)

2001–2003
R-148-000-031-112

$28,000
SJ

Chemotherapy of Gynecological Cancers with Arsenic Compounds

2001-2004
R-148-000-032-112

$85,000
PHo

Pharmacokinetics and Pharmacodynamics of Metastat, an Antiangiogenic Agent in Animals Models : Effect of Combination Chemotherapy

2001-2004
R-148-000-033-112

$40,000
Eli C

Formulation and Process Optimization for Single-Pot Speronization

2001-2004
R-148-000-034-112

$50,700
CL

Dietary Modulation of Drug Transport

2001-2004
R-148-000-035-112

$124,900
LLY

Drug-Related Problems in Patients

2001-2004
R-148-000-036-112

$67,000
CSY

2001

Sub-Total

$395,600.00

A Pilot Study on the Pharmacokinetic Aspect of 4-Dedimethylamino Sancycline, A New Anti-Tumor Agent, in Animal Models

2002-2005
R-148-000-037-112

$43,000
Eli C

Antimalarial Activity of Ferrocenic Chalcones

2002-2004
R-148-000-038-112

$68,600
GML

A Study of Powder Layering for Pharmaceutical Product Development

2002–2005
R-148-000-039-112

$102,000
PHeng/CL

Cellular and Molecular Modulation of Drug Transport by Common Spices in the South East Asian Diet

BMRC Grant 01/1/21/19/142
R-148-000-040-305
1.7.02-30.6.05

$326,150
LLY, GML,
EK (Chemistry)
TTMC (Biochemistry)

Preparation & evaluation of specialty pharmaceuticals excipients

ISP Company Inc.
15.09.02-14.09.05
R-148-000-041-592

$60,378.50
PHeng

Measurement Of Health-Related Quality Of Pharmacy Life(Hrqol) In Singaporean Children With Chronic Diseases: Diabetes & Asthma

2002–2005
R-148-000-043-112

$21,070
LSC

The Human Skin Barrier And Its Intercellular Lipids

2002–2005
R-148-000-044-112

$179,950
CSY

Novel Phosphinegold(I) Thiolate complexes for Anti-Tumor Activity

BMRC 01/1/21/19/119
R-143-000-175-305
R-148-000-062-305
01.07.02-30.06.05

$ 175,940.81
PHo

2002

Sub-Total

$977,089.31

Flavonoid-related cyclin dependent pharmacy kinase inhibitors

2003–2004
R-148-000-042-112

$75,800
GML

Nano-systems to facilitate site-specific drug delivery and enhance cellular drug uptake

2003–2006
R-148-000-045-112

$ 116,500
LLY, WSM(Biol Sci), SJ

Hatchery Technology Advancements for Selected Marine Food Fish Species in Singapore : Development of Inert larval Feeds & Supplements

AVA
01.04.03–31.03.06
R-148-000-046-490

$ 376,100
PHeng

Quality Control of Herbal Medicine and Herbal Medicinal Products

2003–2006
R-148-000-048-112

$ 66,600
KHL

A Phytochemical and Neuropharmacoloical Study of Herbs that Affect the Central Nervous System

2003–2006
R-148-000-049-112

$ 54,430
CWK

Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid, a New Immunosuppressant, in the Asian Renal Transplant Population in Singapore

2003–2006
R-148-000-050-112

$ 74,500
Eli C

Design and Synthesis of Peptides for Immuno-Modulation

2003–2005
R-148-000-051-112

$ 67,495
SJ

The Synthesis and Pharmacological Study of 1,3,5-Triazines

2003–2006
R-148-000-052-112

$ 59,490
CWK

Biopharmaceutics and Pharmacokinetics of Chemotherapeutic Agents and Adjuvants

2003–2006
R-148-000-053-112

$ 97,924
PHo

2003

Sub-Total

$988,839.00

High Performance Extraction and Evaluation of Botanicals for Antimicrobial Activity

2004–2006
R-148-000-055-112

$ 96,950
CLW

Chemical and DNA Evaluation of Botanical Products

2004–2006
R-148-000-056-112

$ 98,000
KHL

In-vitro and In-vivo Stereochemcial Metabolic Interactions Between Warfarin and Selected Complementary Medicines

2004–2007
R-148-000-057-112

$ 61,500
Eli C

Oxidant Properties of Chalcones

2004–2006
R-148-000-058-112

$21,890
GML

The Use of Pharmacoeconomic Approach in the Management of Osteoarthritis in Singapore

2004–2007
R-148-000-059-112

$ 63,050
LSC

Design of Conjugate Peptides and peptidomimetics for Anti-inflammatory Disease

2004–2006
R-148-000-060-112

$ 71,500
SJ

Functional Prediction of Novel Viral Proteins by Support Vector Machines Approach

2004–2006
R148-000-071-112
(R151-000-034-112)

$97,256
CYZ

Implementation and establishment of a joint research group between the laboratory for experimental and applied pharmacokinetic and pharmacodynamic research (LEAP2)

SCS-PU0024
01.01.04-31.03.06
R-148-000-061-305

$53,168
PHo

2004

Sub-Total

$563,314.00

Genomic, proteomic and metabonomic approaches to study the pharmacodynamic responses of chemotherapeutic agents in tumours and their metastases"

2005-2008
R-148-000-063-112

$118,000
PHo

Acridines and related compounds as inhibitors of transcription factor-mediated gene expression

2005-2008
R-148-000-064-112

$119,000
GML

Design of Small Molecular Inhibitors Targeted Towards HER-2 As Therapeutic Agents for Breast Cancer

2005-2007
R-148-000-065-112

S$ 90,000
SJ
GML

Lung Cancer Treatment Using pachymic Acid from Poria Cocos

2005-2008
R-148-050-068-101/
R-148-050-068-133

$ 160,448
LNg

Development of Web-based Server for Protein-Protein Interaction Prediction from Sequence

2005-2007
R148-000-072-112
(R-151-000-036-112)

$38,225
CYZ

Automated Techniques for Model Validation

DSOCL05012
R148-000-073-592
(R151-000-038-592)
01.07.05–30.11.06

$80,000
CYZ

Suspicious Behaviour Detection and Prediction System

2005-2007
R148-000-074-592
(R151-000-039-592)

$31,050
CYZ

Prostate Cancer Prevention by Pachymic Acid

NIH 7R21CA115269-02
2005-2007
R-148-000-087-592

$ 235,953.74
LNg

2005

Sub-Total

$872,676.74

A Comparative Study of the Burden of Illness and Impact on Functional and Pharmacoeconomic outcomes of Osteoarthritis of the Knee and Hip in Two Asian Countries : China and Korea"

2006-2009
R-148-000-075-112

$52,000
LSC

Azaheterylguanidines as Synthons fpr the Preparation of Bioactive Compounds

2006-2008
R-148-000-069-112

$84,000
CWK

Quantification of Surface properties to Optimize Particulate Drug Delivery System

2006-2009
R-148-000-076-112

$132,000
PHeng

Development of Liposome-Based Drug Combination formulations for the Treatment of Cancer

2006-2009
R-148-050-077-101/133

$163,000
GChiu

Regulation of ATP-Binding Cassette (ABC) Transporters

2006-2008
R-148-050-078-101/133

$179,500
REePL

Medicinal Plants of Southeast Asia as Potential Sources of Lead Compounds for New Antiplatelet and Anticoagulant Drugs

2006-2009
R-148-000-079-112

$129,300
KHL

Synthesis of Anti-Viral Agents with Activity Against Influenza

2006-2008
R-148-000-080-101
R-148-000-080-112

$170,400
GML

Simulation and Experimental Study of RAS-Mark Pathway

2006-2008
R-148-000-081-101
R-148-000-081-112

$158,800
CYZ

Design, Synthesis And Evaluation Of Heterocyclic Molecules As Potent And Selective Antagonists Towards Adensine’s Receptor Subtypes

2006-2009
R-148-000-091-101/133

$179,553
GP

Structural Modification of N1-diphenylmethyl-N2-nitrogguanidine for improved neuronal nitric oxide synthase selective inhibition

2006-2009
R-148-000-082-112

$35,350
CWK

"Prediction of MHC-Binding Peptides of Flexible Lengths from Sequence-Derived Structural and Physicochemical Properties"

2006-2008
R-148-000-083-112

$70,010
CYZ

Investigations into the chemopreventive potential of small molecules: Synthesis and mode of action studies"

2006-2009
R-148-000-084-112

$95,080
GML

Establishment of alternative in vivo/in vitro models for pharmaceutical product development

2006-2009
R-148-000-085-112

$100,135
CVLiew

Novel Biomimetic Scaffolds for the Expansion & Injectable Delivery of Human Mesenchymal Stem Cells in Cartilage Repair

SSCC-06-005
2006-2009
R-148-000-086-305

$639,000
REePL

Understanding Structural Toxicity Relationship (STR) of Pharmaceuticals Via Characterization of Reactive Metabolite and Correlation to Hepatotoxicity

2006-2008
R-148-000-088-101/
R-148-000-088-133

$179,000
EChCY

Genetic Polymorphisms of UGT1A9 Gene and Its Influence on the Pharmacokinetics of Mycophenolic Acid in the Asian Renal Transplant Population

2006-2009
R-148-000-092 -112

$128,160
Eli C

2006

Sub-Total

$2,495,288.00

Formulation Research on Organogels and Penetration enhancers for Dermal Drug Delivery

2007-2010
R-148-000-093-112

$129,384
CSY

Nanoparticulate Drug Delivery Systems – nanocapsules

2007-2009
R-148-000-097-112

$163,000
PHo

Design & Synthesis of Novel Inhibitors of Isoprenyl Cysteine Methyltransferase as Potential Anticancer Agents

BMRC 06/1/21/19/487
2007-2009
R-148-000-089-305

$496,800
GML

Innovative Strategy Using Selective Histone Deacetylase Inhibitor in the Management of Rheumatoid Arthritis : A Translational Study

BMRC 06/1/21/19/441
2007-2009
R-148-000-090-305

$379,992
LHS

Development of Liposome formulations for a Protein Kinase C-specific Inhibitor in the Treatment of Cancer

2007-2010
R-148-000-094-123

$35,000
GChiu

Treating Drug-Resistant Cancers by Targeting Multiple Cell survival Pathways: A New Application of Liposome Technology

2007-2010
R-148-000-098-112

$134,600
GChiu

Polymer-lipid Derivatives as Nano-drug Carriers for Anti-Cancer, Water-Insoluble Compounds

EDB Biomed Sci POC
R-148-000-095-414
01.07.07–30.06.08

$257,060
GChiu

Metabonomics Biomarker Study of Alzheimer’s Disease

2007-2010
R-148-000-100-112

$179,000
EChCY

Metabonomic fingerprinting of Neurodegenerative Diseases

2007-2008
R-183-000-199-123

$35,000
EChCY
SK (Biochem)

Folate Receptor targeted Liposome Delivery System As the Enabling Technology to deliver a Potent, naturally-occurring Drug compound for the Treatment of Breast and
Ovarian Cancers

NMRC/1109/2007
R-148-000-101-213
01.09.07-31.08.10

$358,977.35
GChiu

Examining the abioity of Aqueous Garlic
Extracts Isolated from Different Garlic
Varieties to Inhibit Mammary Carcinoma
Metastasis

2007-2011
R-148-000-099-112

$175,000
CEH

2007

Sub-Total

$2,343,813.35

Synthesis of fused polucyclic derivatives and thioxo analogues of 1,3,5-triazine-2, 4-dione as new inhibitors of thymidine phosphorylase for potential use in cancer chemotherapy.

NMRC/NIG/0019/2008
R-148-000-102-275
04.06.08-30.06.10

$197,050
CWK

Identifying Domains of Health-related Quality of Life that are important to Multi-Ethnic Asian Patients with Diabetes Mellitus – An initial Phase in Item Bank Development.

2008-2011
R-148-000-103-133

$179,962
WHL

Metabolic profiles of mesoindigo, an anti-leukemic agent: Identification of the Phase I & II metabolites in the rat, pig and human

2008-2011
R-148-000-104-112

$120,000
PHo

Open Source Java-based Consensus model for Prediction of Harmful Potential of Drugs on the Liver

2008-2010
R-148-000-105-133

$152,721
YCW

Investigation of new lead compounds as Adenosine receptors antagonists and their potential application in the treatment of Neurodegenerative Diseases.

NMRC/NIG/0020/2008
R-148-000-106-275
04.06.08-30.06.10

$200,000
GP

To identify & characterize oxidized protein thiols in human cells.

2008-2011
R-148-000-107-133

$180,000
CEH

Application of Pharmainformatics in the clinical setting: solving drug-related problems through the innovative use of information technology.

2008-2012
R-148-000-108-133

$179,990.70
AC

Developing a Systemic Lupus Erythematosus-specific Health-Related Quality of Life Item Bank for use among Multi-Ethnic Asian Patients.

NMRC/NIG/0039/2008
R-148-000-113-275
30.10.08-30.11.10

$159,659
WHL

Particulate Composite Matrix Delivery System for Enhanced Transmucosal Absorption of Photosensitzer in Oral
Carcinoma

NMRC/1187/2008
R-148-000-114-213
R-148-000-114-216
20.11.08-31.12.11

$480,000
PHeng

2008

Sub-Total

$1,849,382.27

Evaluation of Pharmaceutical Care & Clinical Outcome of Patients with Chronic Illnesses from Pharmacist-led Clinical Services in Singapore.

2009–2012
R-148-000-109-133

$179,950
JL

Characterization of thiol Oxidation of Keap1 in Human Cells

2009-2012
R-148-000-110-112

$33,532.65
CEH

Is Sarcopenic form of Obesity associated with ageing, worse CVD risk & poorer health-related quality of life?

2009-2010
R-148-000-111-646

$49,990
WHL

Evaluation of Multidisciplinary, Multifaceted Antimicrobial Stewardship Program in Singapore Hospitals

2009-2012
R-148-000-112-133

$179,200
CTeng

Development of new capabilities in assessing hepatotoxic potential of complementary & alternative medicine (CAM) implicated in drug-induced liver injury (DILI)

HSA-NUS
R-148-000-115-490
06.05.09-31.03.11

$119,700
KHL

Elucidation of the Action of Cinnamaldehydes and Shogoals on the Keap1-Nrf2-ARE Pathway

2009-2012
R-148-000-116-112

$127,093
CEH

Exploring the Role of Tyrosine Kinase Tyro3 in Hepatocellular Carcinoma

2009-2012
R-148-000-117-133

$180,000
HHK

Evaluation of compounds with electrophilic propensities as potential inhibitors of the thioredoxin system

NMRC/NIG/0050/2009
R-148-000-118-275
23.05.09-30.06.11

$200,000
CEH

Prevalence of Vitamin D Insufficiency and Deficiency in Chronic Kidney Disease Patients in Singapore

2009-2012
R-148-000-119-133

$180,000
P How

Pharmacoeconomic Evaluation of Treatments for Chronic Diseases

2009-2012
R-148-000-120-133
16.09.09-15.09.12

$180,000
KO Yu, Nancy

Apoptosis Signalling Mechanism in Mitochondria

2009-2012
R-148-000-121-133
01.09.09-31.08.12

$1,200,000
Victor Yu

Therapeutic Targeting of Wnt Signalling in Osteosarcoma

2009-2010
R-148-000-122-112
R-148-001-122-112
01.12.09-30.11.2010

$43,949.39
REePL

Exploring Mesenchymal Stem Cell-Derived Conditioned Medium as Hepatoprotective Agents Against Drug-induced Liver Injuries

NMRC/NIG/1001/2009
R-148-000-125-275
18.11.09-31.12.2011

$170,000
Ho Han Kiat

Prevalence and Clinical Impact of Adverse Drug-drug Interactions in Cancer Patients

NMRC/NIG/09may028
R-148-000-130-275
18.11.09-31.12.2011

$164,100
KO Yu, Nancy

In Vitro Hair Follicular Unit Reconstruction with Natural Appearance and Functions by Tissue Engineering method

NMRC/NIG/09may029
R-148-000-131-275
18.11.09-31.12.2011

$167,110
Kang L

2009

Sub-Total

$3,160,675.65

A Benchmark Project on Early and Late Mortality from Chemotherapy

2010-2012
R-148-000-123-133
01.01.10-31.12.12

$180,000
Lita Chew

Examination of Cardiovascular Wellness of Diabetes in Singapore

2010-2013
R-148-000-124-133
15.03.2010-14.03.2013

$180,000
JChang

Developing a platform for Physiological Based Pharmacokinetic and Pharmacodynamic Modelling of Innovative Therapies with Positive Emission Tomography (PET) and Computed Tomographic Scanning (CT)

CFG10P14
R-148-000-126-646
01.02.2010-31.01.2012

$25,000
P Ho

Prevalence of Vitamin D Deficiency in Pre-Dialysis Chronic Kidney Disease Patients in Singapore

NKFRC/2009/07/15
R-148-000-127-592
01.01.2010-31.12.2012

$40,000
P How

A study on the Role of Intercellular Transfer of Cytosolic Materials by Mesenchymal Stromal Cells for the Anti-Apoptotic Support in Hematopoietic Stem Cell Expansion and Marrow Repair

SSCC/09/021
01.01.2010-31.12.2012

$747,000
G Chiu (co-PI)

Jan 2010

Sub-Total

$1,172,000.00

Strategic Functionalizations of Carbon Nanotubes for transport, protection and delivery of drugs

FRC 2009 R2
R-148-000-129-112
01.04.2010-31.03.2013

$165,055
G Pastorin

Multifunctional polymeric nanoparticulate drug delivery systems for the treatment of metastatic tumors

FRC 2009 R2
R-148-000-128-112
25.02.2010-26.02.2013

$122,437
P Ho

Nanoneedle Devices for Transdermal Vaccine Delivery

MOE T2
R-398-000-068-112
01.04.2010-31.03.2013

$1,017,020
G Pastorin

Feb 2010

Sub-Total

$1,304,512.00

Dissolving Microneedles for Biological Drug Delivery

Start-up grant
24.03.2010-23.2.2012

$90,000
Kang L

Mar 2010

Sub-Total

$90,000.00

Design, Synthesis and mechanistic studies of isoindigos as multi-targeting anti-cancer agents

FRC 2010 R1
R-148-000-132-112
21.06.2010-20.06.2013

$85,000
GML

Molecular profiling of fecal microRNAs for the detection of colorectal cancer

FRC 2010 R1
R-148-000-133-112
15.06.010–14.06.2013

$175,000
HHK

Jun 2010

Sub-Total

$260,000.00

Metabonomic phenotyping of human nephrolithiasis

FRC 2010 R2
R-148-000-135-112
01.01.2011-31.12.2013

$139,433
EChCY

Usage of medicinal plants in South East Asia

FRC 2010 R2
R-148-000-137-112
01.09.2010-31.08.2013

$72,000
KHL

Virtual screening of large chemical libraries to discover novel neuraminidase inhibitors against Influenza A virus

FRC 2010 R2
R-148-000-136-112
01.09.2010-31.08.2012

$43,157
YCW

Jul 2010

Sub-Total

$254,590.00

Preclinical studies on pharmacodynamics, disposition and systemic delivery of a novel epigenetic antitumor agent, 3-Deazaneplanocin A alone or in combination with Trichostatin A

FRC 2010 R1
R-148-000-134-112
01.08.2010-31.07.2013

$148,000
Eli C

A systematic characterization of the intrinsic drug metabolism capacity of hepatocytes differentiated from stem cells

SSCC/10/026
01.09.10-31.08.2013

$243,783
EChCY

Aug 2010

Sub-Total

$391,783.00

Quantum dot-based microfluidic device for determining the etiology of Rhinitis

SERC 102/152/0016
R-148-001-435-305
01.05.10-30.04.2013

$272,875
G Pastorin & HHK

Sep 2010

Sub-Total

$272,875.00

Development of a chromatographic method as a non-radioactive alternative assay for the mitochondrial enzyme Propionyl-CoA Carboxylase

Start-up Grant
R-148-000-139-750
15.11.10-14.11.2012

$90,000
Kang TS

Investigations of Selected Medicinal Plants

Leeward Pacific PL
R-148-000-140-592
1.12.10-30.11.2012

$395,472
KHL

Nov 2010

Sub-Total

$485,472.00

Optimization of a Dosing Regime for Sunitinib in Metastatic Renal Cell Carcinoma (mRCC) Treatment Through Pharmacokinetic Monitoring to Achieve Better Efficacy and Safety Profile

S’pore Cancer Society
R-148-00-145-592
15.12.2010-14.12.2011

$99,700
AC

Dec 2010

Sub-Total

$99,700.00

Development of combined molecular modelling and machine learning methods for searching multi-target drugs and serious adverse drug reactions

NUS Bridging Grant
R-148-000-141-750/
R-148-000-141-646
01.01.11-31.12.2013

$288,813
CYZ

Synthesis and evaluation of inhibitors of isoprenylcysteine carboxyl methyltransferase, a novel therapeutic target for oncogenesis

BMRC
R-148-000-147-305
01.01.11-31.12.2013

$677,890
GML

Implementing a Monitoring Tool in the Nursing Home to Aid Prescribing of Psychotropic Agents in Residents with Dementia

VISA Grant
R-148-000-142-290
15.01.2011-14.01.2013

$20,000
CSY

Design and synthesis of small molecules that target nuclear co-repressor (N-CoR) protein in acute promyelocytic leukemia

NMRC
17.01.11-31.1.2013

$97,720
GML

Jan 2011

Sub-Total

$1,084,423.00

Towards the development of selective chemotherapeutics

Start-up Grant
R-148-000-146-133
01.02.2011-01.01.2014

$748,900
CLL

Financial Constraints in elderly to afford novel anticancer therapies – A prevalence evaluation

VISA Grant
R-148-000-143-290
14.02.2011-13.01.2013

$18,488
AC

Cost-effectiveness of home-based medication reviews in reducing health services utilization & drug-related problems & improving health-related quality of life among multi-ethnic Singaporeans

MOH CSR
R-148-000-154-221
17.02.11-17.02.2013

$163,841
WHL

Feb 2011

Sub-Total

$931,229.00

Role of Secreted Wnt antagonists on osteosarcoma invasion and metastasis

FRC
R-148-000-150-112
01.04.2011-31.03.2014

$169,600
REePL

Synthetic Polymeric Derivatives as Modulators of Drug Transport Mechanisms

FRC
R-148-000-151-112
01.04.2011-31.03.2014

$125,946
G Chiu

Apr 2011

Sub-Total

$295,546.00

Novel gene-enhanced peptide-PEG hybrid hydrogels for cartilage repair

MOE
R-148-000-152-112
01.06.2011-31.5.2014

$130,000
REePL

Exploration of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Agonist in Neurodegeneration Therapy – A Therapeutic Enigma

NMRC EDG
R-148-000-158-275
15.06.2011-31.07.2013

$164,000
PHo

June 2011

Sub-Total

$294,000.00

Exploring Host Metabotype - Microbiome Interaction: A Silent Phenotype in Drug Disposition and Toxicity

BMRC
R-148-000-144-305
R-148-000-144-331 (IRC)
01.07.2011-30.06.2014

$324,330
EChCY

Jul 2011

Sub-Total

$324,330.00

Innovations in Processing of Specialties and Pharmaceuticals (iPSP) Programme – Capability Development Fund

A*Star-SERC
R-148-000-157-305
R-148-000-157-331 (IRC)
01.08.2011-31.07.2014

$642,712
PHeng (Co-PI)

Fragment-based Dual Targeted Heterocycles as Potential Anticancer Agents

FRC
R-148-000-153-112
01.08.2011-31.07.2014

$145,800
CWK

Novel Transdermal Drug Delivery Systems for Neuropathic Pain

FRC
R-148-000-155-112
01.08.2011-31.07.2014

$177,991
CSY

Effects of a Community Pharmacist-led Medication Therapy Management Service on the Elderly with Chronic Diseases in Singapore

Alice Lim Grant (External grant)
01.08.2011 – 30.0.2013

$15,000
JLee

Aug 2011

Sub-Total

$981,503.00

Active Targeting of Tuberculosis via Novel Nanotherapeutics

NMRC
R-148-000-159-213
R-148-000-159-216 (IRC)
01.09.2011-31.8.2014

$618,300
REePL

Sep 2011

Sub-Total

$618,300.00

A Benchmark Project on Medication Errors in Singapore

Start-up Grant
R-148-000-156-133
01.10.2011-30.09.2014

$180,000
WLL

Development of New Capabilities in assessing hepatotoxic potential of complementary and alternatives medicine (CAM) implicated in drug-induced liver injury (DILI)

HSA Grant
R-148-001-115-490
R-148-001-115-495 (IRC)
12.10.2011–31.03.2012

$50,000(incl.IRC)
KHL

Oct 2011

Sub-Total

$230,000.00

Investigation of the physiological roles of MOAP-1 in mitochondrial apoptosis signalling pathway

NMRC IRG
R-148-000-161-213
R-148-000-161-216 (Project’s IRC)
R-148-000-710-733 (PI’s IRC)
19.12.2011–31.12.2014

$1,251,064.10
(+IRC of up to 20%)
Victor Yu

Dec 2011

Sub-Total

$1,251,064.10

Creation of Passages through Skin by Microneedles for Drug Delivery

EDB-IPP
R-148-000-167-592
9.01.2012 – 8.01.2016

$100,045
KLifeng

Human Bone Systems Biology Model

EDB-IPP
01.01.12 – 31.12.2015

$100,000
PHo

Jan 2012

Sub-Total

$200,045.00

Clinical predictors for chemotherapy induced nausea and vomiting among head and neck cancer Asian patients receiving cisplatin

MSD IISP Grant
R-148-000-160-592
01.04.2012-31.03.2014

$81,600 (incl.IRC)
Alex Chan

Clinical and biological determinants for Chemotherapy-Associated cognitive changes in Breast cancer patients

FRC 2012 R1
01.04.2012-31.03.2015

$126,370
Alex Chan

Improving PADEL-Descriptor, a software for calculating descriptors, by increasing number of molecular descriptors and using GPGPU programming to improve computational speed

FRC 2012 R1
01.04.2012-31.03.2015

$129,382
YapCW

The development of nano-probes and imaging techniques for subcellular high resolution imaging

FRC 2012 R1
R-148-000-164-112
01.04.2012-31.03.2015

$142,000
G Pastorin

Molecular pharmaceutics for tropical diseases

EDB IPP
R-148-000-163-592
01.04.2012-31.03.2016

$21,400
PHo

Pharmacogenetics Study of New-Onset Diabetes After Transplantation in Singapore Asian Renal Transplant Patients Receiving Calcineurin Inhibitor-Based Immunosuppression

NKF
R-148-000-176-592
01.04.2012-31.12.2014

$40,000
YauWP

Assessment of the toxicological profiles and biodegradability of functionalized nanomaterials for applications in nanomedicine

MERLION Project
R-148-000-162-133
01.04.2012-31.03.2014

$30,000
G Pastorin

Apr 2012

Sub-Total

$570,752.00

Discovery of Biologically Active Novel Molecules for Cancer and Muscular Dystrophy Using Fragment Based Screening

NUS Start-up grant
01.09.12 – 31.08.2015

$862,000
Brian W Dymock

Dynamic Combinatorial mass spectrometric-based approach to the rapid discovery of novel substrates for JmjC histone demethylases

NUS Start-up grant
01.09.12 – 31.08.2015

$180,000
Esther Woon

A study of medicinal plants growing in Singapore to meet unmet medical needs

Collaboration with Leeward Pacific Pte Ltd
R-148-000-172-592
R-148-000-172-598 (IRC)
19.09.12 – 18.09.2015

$1,322,520
KHL

The effectiveness of Pharmacist-involved Collaborative Care Model in the Management of Patients with Diabetes Mellitus in Singapore

HSR Grant
R-148-000-177-511
R-148-000-177-512 (IRC)
10.09.12 – 9.9.2014

$1,192,000 (incl.20% IRC)
JLee

Sep 2012

Sub-Total

$3,556,520.00

Innovative strategy using stilbene analogues of resveratrol in the management of inflammatory diseases: A proof-of-concept study

NUS Start-up grant
01.10.12 – 30.09.2015

$180,000
L Haishu

A comparison of Patient-reported, Economic and Clinical Outcomes between Hemodialysis and Peritoneal Dialysis Patients in a Multi-Ethnic Asian Population

FRC Grant
01.10.2012 -30.9.2015

$125,200
PHow

Oct 2012

Sub-Total

$305,200.00

Synthesis and mechanistic studies of novel agents for Hepatocellular Carcinoma

FRC Grant
01.11.2012 -31.10.2015

$50,000
GoML

Nov 2012

Sub-Total

$50,000.00

Understanding the role of MOAP-1 in normal ageing and catastrophic brain injury. (Co-PI)

MOE T2
R-148-000-173-112
01.01.2013-31.12.2015

$110,000
VYu

Understanding the interplay between cell death pathways and HCV infection. (Co-PI)

MOE T2
R-148-000-179-113
01.01.2013-31.12.2015

$180,000
VYu

Jan 2013

Sub-Total

$290,000.00

Improved virtual screening method and discovery of Multitarget kinase inhibitors

FRC Grant
01.02.2013-31.01.2016

$169,500
CYZ

Stereoselective transport of pioglitazone through blood-brain barrier in the treatment of Alzheimer’s disease

FRC Grant
01.02.2013-31.01.2016

$177,101
PHo

Novel Method of Fabricating Large-Area Microneedle Arrays

NRF POC
R-148-000-178-281
16.02.13-15.02.2014

$216,000
KLF

Unravelling the chemistry of catecholic building blocks: Biomimetic approaches to new materials

A*Star PSF
R-148-000-182-305
01.02.2013-31.01.2016

$379,680 (inc.20% IRC)
CLL

A fast micro-Raman system for high-resolution chemical imaging in biomedicine. (Co-PI)

A*Star PSF
R-148-000-183-305
01.02.2013-31.01.2016

$133,200 (inc.20% IRC)
PHo

Feb 2013

Sub-Total

$1,075,481

Evaluation and characterization of the anti-invasive and anti-inflammatory properties of compounds with natural origins and their novel derivatives

FRC Grant
01.04.2013-31.03.2016

$179,926
CEH

Apr 2013

Sub-Total

$179,926.00

 

Sources of funding

NUS Office of the Deputy President (Research and Technology)

A*Star - Agency for Science, Technology and Research

National Research Foundation

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