SEMINAR ANNOUNCEMENT

PhD Thesis Defence Seminar
(Conducted via Video Conferencing)
Cross-cultural adaptation, validation and application of health-related quality of life instruments in Asians in Singapore

by

Mr Luo Nan
Department of Pharmacy
National University of Singapore

on

Date: Tthursday, 20th November 2003
Time: 1430 - 1530 hrs
Venue: NUS Global Classroom, Computer Centre, 3rd Floor


To view the map, please click here

The seating capacity is limited to only 32. For those who are interested to attend, please email Chai Hun at for reservation of seats by 15th November 2003.

Synopsis:

The project aimed to culturally adapt and validate the EQ-5D self-report questionnaire (EQ-5D), the Schizophrenia Quality of Life Scale (SQLS) and/or the Health Utilities Index Mark 3 (HUI3) and to study the health-related quality of life (HRQoL) in Singaporeans with mental disorders. These instruments were translated/modified to Singaporean languages and administered to Singaporeans with various diseases. Psychometric properties were assessed in terms of feasibility, validity, reliability, responsiveness and/or measurement equivalence. HRQoL in patients with schizophrenia or anxiety disorders was compared with that in other populations and factors influencing HRQoL were identified using linear regression models. Generally, the EQ-5D, HUI3 and SQLS appear to be feasible, valid and/or reliable instruments in study populations. Singaporeans with schizophrenia or anxiety disorders experience clinically important reductions in HRQoL and both clinical variables and socio-demographics influence these patients' HRQoL. In conclusion, extraneous HRQoL instruments can be useful in Singapore after cultural adaptation and validation.


Key Words: Anxiety disorders; Health status; Quality of life; Reproducibility of results; Singapore; Schizophrenia